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Biological forms have inherent limitations which may or may not be able to be overcome through medical interventions or engineering.As of 2009, natural selection has developed biological immortality in at least one species, the jellyfish Certain scientists, futurists, and philosophers, such as Ray Kurzweil, advocate that human immortality is achievable in the first few decades of the 21st century, while other advocates believe that life extension is a more achievable goal in the short term, with immortality awaiting further research breakthroughs further into an indefinite future.Aubrey de Grey, a researcher who has developed a series of biomedical rejuvenation strategies to reverse human aging (called SENS), believes that his proposed plan for ending aging may be implementable in two or three decades.

No definitive work has yet demonstrated that telomerase can be used in human somatic cells to prevent healthy tissues from aging.By definition, all causes of death must be overcome or avoided for physical immortality to be achieved.There are three main causes of death: aging, disease and trauma.Genes associated with type 1 diabetes and certain types of cancer have been discovered allowing for new therapies to be developed.Artificial devices attached directly to the nervous system may restore sight to the blind.

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